Synergism in several physical properties as realized in many mixed surfactant reverse micellar (RM) systems often manifests optimum hydrophilic–lipophilic balance (HLB), interdroplet interaction, or both. Such synergism is often desired for specific applications of RM systems; however, a proper rationale on the effect of such phenomenon imparted on the structure, dynamics, and activity of water molecules in RM waterpool is strongly demanded. In the present contribution we have investigated how the optimum HLB condition of mixed RM composed two nonionic surfactants (Igepal 210 and Igepal 630) affects the physical properties of entrapped water molecules in the RM waterpool. The studied mixed RM exhibits synergistic water solubilization behavior as a function of the mixing ratio with a maximum in solubilization capacity being reached at XIg630 = 0.3. Dynamic light scattering (DLS) studies show a bimodal …